发明申请
US20110263862A1 PIPERIDINE DERIVATIVE, PIPERAZINE DERIVATIVE AND AGENT FOR TREATMENT OF DISEASE INVOLVING CENTRAL NERVOUS SYSTEM DISORDERS 审中-公开
哌啶衍生物,哌嗪衍生物和治疗涉及中枢神经系统疾病的疾病

  • 专利标题: PIPERIDINE DERIVATIVE, PIPERAZINE DERIVATIVE AND AGENT FOR TREATMENT OF DISEASE INVOLVING CENTRAL NERVOUS SYSTEM DISORDERS
  • 专利标题(中): 哌啶衍生物,哌嗪衍生物和治疗涉及中枢神经系统疾病的疾病
  • 申请号: US13126158
    申请日: 2009-10-26
  • 公开(公告)号: US20110263862A1
    公开(公告)日: 2011-10-27
  • 发明人: Shiro MitaNaoyuki Kobayashi
  • 申请人: Shiro MitaNaoyuki Kobayashi
  • 申请人地址: JP Kobe-shi, Hyogo
  • 专利权人: M'S Science Corporation
  • 当前专利权人: M'S Science Corporation
  • 当前专利权人地址: JP Kobe-shi, Hyogo
  • 优先权: JP2008-276046 20081027
  • 国际申请: PCT/JP2009/068341 WO 20091026
  • 主分类号: C07D221/00
  • IPC分类号: C07D221/00
PIPERIDINE DERIVATIVE, PIPERAZINE DERIVATIVE AND AGENT FOR TREATMENT OF DISEASE INVOLVING CENTRAL NERVOUS SYSTEM DISORDERS
摘要:
A novel piperidine derivative and a novel piperazine derivative which are useful as novel sigma receptor ligands, and an agent for treatment of diseases involving a central nervous system disorders, said agent containing one of the compound as an active ingredient. The agent contains a compound represented by general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: wherein X represents an alkylene group having 1 to 5 carbon atoms, and the alkylene group may be substituted by one or more alkyl groups each having 1 to 2 carbon atoms; Y represents a carbon atom or a nitrogen atom; and R1 and R2 each independently represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 2 carbon atoms or an alkoxy group having 1 to 2 carbon atoms.
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