发明申请
- 专利标题： SUGAR CHAIN ADDED GLP-1 PEPTIDE
- 专利标题（中）： 糖链添加GLP-1肽
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申请号： US13152082申请日： 2011-06-02
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公开(公告)号： US20110245166A1公开(公告)日： 2011-10-06
- 发明人: Yasuhiro KAJIHARA , Takashi TSUJI , Izumi SAKAMOTO , Yuri NAMBU , Kazuhiro FUKAE , Katsunari TEZUKA , Hiroaki ASAI
- 申请人： Yasuhiro KAJIHARA , Takashi TSUJI , Izumi SAKAMOTO , Yuri NAMBU , Kazuhiro FUKAE , Katsunari TEZUKA , Hiroaki ASAI
- 申请人地址： JP OSAKA-SHI
- 专利权人： OTSUKA CHEMICAL HOLDINGS CO., LTD
- 当前专利权人： OTSUKA CHEMICAL HOLDINGS CO., LTD
- 当前专利权人地址： JP OSAKA-SHI
- 优先权： JP2007-16095 20070619
- 主分类号： A61K38/26
- IPC分类号： A61K38/26 ; C07K14/605 ; A61P3/10
摘要：
The present invention relates to an oligosaccharide chain added GLP-1 peptide that has higher stability in blood than that of GLP-1 and, preferably, exhibits higher activity of controlling blood-sugar levels than that of GLP-1. The present invention relates to an oligosaccharide chain added GLP-1 peptide having GLP-1 activity, wherein at least one amino acid is substituted with an oligosaccharide chain added amino acid, in: (a) GLP-1; (b) a peptide having the amino acid sequence of GLP-1 with deletion, substitution or addition of one or several amino acids; or (c) a GLP-1 analog.
公开/授权文献
- US08507429B2 Sugar chain added GLP-1 peptide 公开/授权日：2013-08-13
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