发明申请
- 专利标题： ISONICOTINAMIDE OREXIN RECEPTOR ANTAGONISTS
- 专利标题（中）： 异烟肼受体拮抗剂
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申请号： US13124568申请日： 2009-10-26
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公开(公告)号： US20110201591A1公开(公告)日： 2011-08-18
- 发明人: Jeffrey M. Bergman , Paul J. Coleman , Mamio Christa Mattern , Swati P. Mercer , Thomas S. Reger , Anthony J. Roecker
- 申请人： Jeffrey M. Bergman , Paul J. Coleman , Mamio Christa Mattern , Swati P. Mercer , Thomas S. Reger , Anthony J. Roecker
- 国际申请： PCT/US2009/061987 WO 20091026
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; C07D401/14 ; C07D213/81 ; C07D401/04 ; C07D401/12 ; C07D417/14 ; A61K31/444 ; A61K31/4418 ; A61K31/4439 ; A61P3/04 ; A61P25/00
摘要：
The present invention is directed to isonicotinamide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
公开/授权文献
- US08592457B2 Isonicotinamide orexin receptor antagonists 公开/授权日：2013-11-26
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