Invention Application
- Patent Title: POST IRRADIATION SHELF-STABLE DUAL PASTE DIRECT INJECTABLE BONE CEMENT PRECURSOR SYSTEMS AND METHODS OF MAKING SAME
- Patent Title (中): 后喷射保护性双稳态直接注射骨水泥前体系统及其制造方法
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Application No.: US12970393Application Date: 2010-12-16
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Publication No.: US20110152195A1Publication Date: 2011-06-23
- Inventor: Donal O'Mahony , Venkat R. Garigapati , Adrian Sun Wai , Brian Hess , Matthew E. Murphy
- Applicant: Donal O'Mahony , Venkat R. Garigapati , Adrian Sun Wai , Brian Hess , Matthew E. Murphy
- Applicant Address: US NJ Mahwah
- Assignee: Howmedica Osteonics Corp.
- Current Assignee: Howmedica Osteonics Corp.
- Current Assignee Address: US NJ Mahwah
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C08K3/32 ; C04B12/02 ; A61K47/02 ; A61P19/00 ; A61B17/56

Abstract:
The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas.
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