Invention Application
- Patent Title: TREATMENT OF MICROBIAL INFECTIONS
- Patent Title (中): 治疗微生物感染
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Application No.: US12865336Application Date: 2009-01-29
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Publication No.: US20110150918A1Publication Date: 2011-06-23
- Inventor: Timothy Foster , Judy Higgins , Elisabet Josefsson , Joan Geoghegan , Carlake Andersson
- Applicant: Timothy Foster , Judy Higgins , Elisabet Josefsson , Joan Geoghegan , Carlake Andersson
- Priority: GB0801768.3 20080131; IE2008/0070 20080131
- International Application: PCT/EP09/51033 WO 20090129
- Main IPC: A61K39/085
- IPC: A61K39/085 ; C12N15/63 ; C12N1/00 ; A61P37/04 ; A61P31/04
Abstract:
The present invention is directed to improved microbial antigen vaccines, pharmaceutical compositions, immunogenic compositions and antibodies and their use in the treatment of microbial infections, particularly those of bacterial origin, including Staphylococcal origin. Ideally, the present invention is directed to a recombinant staphylococcal MSCRAMM or MSCRAMM-like proteins, or fragment thereof, with reduced binding to its host ligand, for use in therapy.
Information query
