A mounting mechanism for attaching a data storage device to a chassis includes a housing, first and second driving members, a latching member, first, second, and third elastic members. The housing defines first, second and third sliding paths therein. The first and third sliding paths extend along a first direction of the housing for receiving the first driving member and the latching member. The second sliding path extends along a second direction of the housing substantially perpendicular to the first direction for receiving the second driving member. The first driving member forms an inclined guiding surface at an end thereof outside the housing. When the guiding surface is pressed down, the driving member moves inward, driving the second driving to move and disengage from the latching member, and the latching member moves along the first direction by an elastic force of the third elastic member.