A honeycomb structure includes at least one honeycomb unit. The honeycomb unit includes a first region, a second region different from the first region, an inorganic binder, and zeolite. The first region extends from one end of the honeycomb unit over approximately 30% or more and approximately 70% or less of an overall length of the honeycomb unit in the longitudinal direction. The zeolite includes a first zeolite and a second zeolite. The first zeolite is ion-exchanged with a first metal and has a mass content. The second zeolite is ion-exchanged with a second metal and has a mass content that is smaller than the mass content of the first metal in the first region and larger than the mass content of the first metal in the second region.