发明申请
US20110046367A1 3-3-DI-SUBSTITUTED-OXINDOLES AS INHIBITORS OF TRANSLATION INITIATION
有权
3-3-DI替代的氧化物作为翻译启动的抑制剂
- 专利标题： 3-3-DI-SUBSTITUTED-OXINDOLES AS INHIBITORS OF TRANSLATION INITIATION
- 专利标题（中）： 3-3-DI替代的氧化物作为翻译启动的抑制剂
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申请号： US12916956申请日： 2010-11-01
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公开(公告)号： US20110046367A1公开(公告)日： 2011-02-24
- 发明人: José A. Halperin , Amarnath Natarajan , Huseyin Aktas , Yun-Hua Fan , Han Chen
- 申请人： José A. Halperin , Amarnath Natarajan , Huseyin Aktas , Yun-Hua Fan , Han Chen
- 申请人地址： US MA Cambridge
- 专利权人： President and Fellows of Harvard College
- 当前专利权人： President and Fellows of Harvard College
- 当前专利权人地址： US MA Cambridge
- 主分类号： C07D498/06
- IPC分类号： C07D498/06 ; C07D209/34 ; C07D403/06 ; C07D417/10 ; C07D403/04 ; C07D409/04
摘要：
Compositions and methods for inhibiting translation using 3-(5-tert-Butyl-2-Hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using 3-(5-tert-butyl-2-hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are described.
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