发明申请
- 专利标题： NOVEL PYRROLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
- 专利标题（中）： 新型吡咯烷酮衍生物和包含其的药物组合物
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申请号： US12450548申请日： 2008-03-28
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公开(公告)号： US20100210632A1公开(公告)日： 2010-08-19
- 发明人: Hiroyuki Kai , Shunji Shinohara , Takayuki Kameyama
- 申请人： Hiroyuki Kai , Shunji Shinohara , Takayuki Kameyama
- 优先权： JP2007-091624 20070330
- 国际申请： PCT/JP2008/056107 WO 20080328
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; C07D413/10 ; A61K31/42 ; C07D401/06 ; A61K31/4439 ; C07D487/04 ; C07D413/14 ; A61K31/5377 ; A61P19/02
摘要：
The present invention provides a compound represented by the formula (I): wherein R1, R2, R3, Z1, Z2, Ra, Rb, q, A and n are as defined in the description, a pharmaceutically acceptable salt or solvate thereof. The compound is useful as P2X3 and/or P2X2/3 receptor antagonist.
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