发明申请
US20100209344A1 Radio-methyl Vorozole and Methods for Making and Using the Same
有权
无线电甲基Vorozole及其使用方法
- 专利标题： Radio-methyl Vorozole and Methods for Making and Using the Same
- 专利标题（中）： 无线电甲基Vorozole及其使用方法
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申请号： US12704114申请日： 2010-02-11
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公开(公告)号： US20100209344A1公开(公告)日： 2010-08-19
- 发明人: Sung Won Kim , Anat Biegon , Joanna S. Fowler
- 申请人： Sung Won Kim , Anat Biegon , Joanna S. Fowler
- 申请人地址： US NY Upton
- 专利权人： Brookhaven Scince Associates, LLC
- 当前专利权人： Brookhaven Scince Associates, LLC
- 当前专利权人地址： US NY Upton
- 主分类号： A61K51/04
- IPC分类号： A61K51/04 ; C07D403/10 ; A61K49/10 ; G01N33/573
摘要：
Radiotracer vorozole compounds for in vivo and in vitro assaying, studying and imaging cytochrome P450 aromatase enzymes in humans, animals, and tissues and methods for making and using the same are provided. [N-radio-methyl] vorozole substantially separated from an N-3 radio-methyl isomer of vorozole is provided. Separation is accomplished through use of chromatography resins providing multiple mechanisms of selectivity.
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