Invention Application
US20100184031A1 NOVEL ADIPOCYTOKINE VISFATIN/PBEF1 IS AN APOPTOSIS ASSOCIATED FACTOR INDUCED IN MONOCYTES DURING IN VIVO HIV-1 INFECTION
审中-公开
新型ADIPOCYTOKINE VISFATIN / PBEF1是在HIV感染HIV感染期间诱发的单克隆抗体相关因子
- Patent Title: NOVEL ADIPOCYTOKINE VISFATIN/PBEF1 IS AN APOPTOSIS ASSOCIATED FACTOR INDUCED IN MONOCYTES DURING IN VIVO HIV-1 INFECTION
- Patent Title (中): 新型ADIPOCYTOKINE VISFATIN / PBEF1是在HIV感染HIV感染期间诱发的单克隆抗体相关因子
-
Application No.: US12451864Application Date: 2008-06-05
-
Publication No.: US20100184031A1Publication Date: 2010-07-22
- Inventor: Geert Raes , Patrick De Baetselier , Rafael Van den Bergh , Guido Vanham
- Applicant: Geert Raes , Patrick De Baetselier , Rafael Van den Bergh , Guido Vanham
- International Application: PCT/EP2008/057025 WO 20080605
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The present invention relates to the use of monocyte markers for diagnostic, prognostic or theranostic applications during diseases and syndromes caused by HIV infection. More specifically, it relates to a method comprising isolation of monocytes and determining gene expression, preferably PBEF1 gene expression. The method is useful to determine the evolution of the disease or can be used to evaluate the efficacy of a treatment.
Information query
