发明申请
US20100120045A1 GENETIC VARIANTS USEFUL FOR RISK ASSESSMENTS OF CORONARY ARTERY DISEASE AND MYOCARDIAL INFARCTION
审中-公开
有用于冠状动脉疾病和心肌梗塞风险评估的遗传变异
- 专利标题： GENETIC VARIANTS USEFUL FOR RISK ASSESSMENTS OF CORONARY ARTERY DISEASE AND MYOCARDIAL INFARCTION
- 专利标题（中）： 有用于冠状动脉疾病和心肌梗塞风险评估的遗传变异
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申请号： US12598180申请日： 2008-04-30
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公开(公告)号： US20100120045A1公开(公告)日： 2010-05-13
- 发明人: Anna Helgadottir , Gudmar Thorleifsson
- 申请人： Anna Helgadottir , Gudmar Thorleifsson
- 申请人地址： IS Reykjavik
- 专利权人： DECODE GENETICS EHF
- 当前专利权人： DECODE GENETICS EHF
- 当前专利权人地址： IS Reykjavik
- 优先权： IS8639 20070430
- 国际申请： PCT/IS08/00011 WO 20080430
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C07H21/00
摘要：
The invention relates to methods of risk assessment and diagnosis of susceptibility to coronary artery disease and myocardial infarction, by assessing the presence or absence of alleles of certain polymorphic markers found to be associated with coronary artery disease and myocardial infarction. The invention also relates to methods for use of such polymorphic markers for predicting drug response to drugs for treating cardiovascular disease, or for monitoring the effectiveness of such drugs. The invention further relates to kits encompassing reagents for use in these methods.
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