Invention Application
- Patent Title: CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS
- Patent Title (中): 化合物受体结合杂环化合物
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Application No.: US12612488Application Date: 2009-11-04
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Publication No.: US20100105915A1Publication Date: 2010-04-29
- Inventor: Gary J. BRIDGER , Renato Skerlj , Ai Kaller , Curtis Harwig , David Bogucki , Trevor R. Wilson , Jason Crawford , Ernest J. Mceachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols
- Applicant: Gary J. BRIDGER , Renato Skerlj , Ai Kaller , Curtis Harwig , David Bogucki , Trevor R. Wilson , Jason Crawford , Ernest J. Mceachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols
- Main IPC: C07D401/02
- IPC: C07D401/02
Abstract:
Heterocyclic compounds that bind chemokine receptors and inhibit the binding of their natural ligands are disclosed. The invention compounds are protective against infection by HIV and exert effects characteristic of antagonists to the CXCR4 receptor.
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