发明申请
- 专利标题： Kinase inhibitors and methods of their use
- 专利标题（中）： 激酶抑制剂及其使用方法
-
申请号： US12584158申请日： 2009-08-31
-
公开(公告)号： US20100056576A1公开(公告)日： 2010-03-04
- 发明人: Matthew T. BURGER , Wooseok HAN , Jiong LAN , Gisele NISHIGUCHI
- 申请人： Matthew T. BURGER , Wooseok HAN , Jiong LAN , Gisele NISHIGUCHI
- 主分类号： A61K31/444
- IPC分类号： A61K31/444 ; C07D401/12
摘要：
New compounds, compositions and methods of inhibition of Provirus Integration of Maloney Kinase (PIM kinase) activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one PIM kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer.
公开/授权文献
- US08329732B2 Kinase inhibitors and methods of their use 公开/授权日：2012-12-11
信息查询
IPC分类:
