发明申请
US20100056545A1 NOVEL PHENYLACETATE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREOF AND COMPOSITION FOR PREVENTION OR TREATMENT OF DISEASES INDUCED BY ACTIVATION OF T-TYPE CALCIUM ION CHANNEL CONTAINING THE SAME AS AN ACTIVE INGREDIENT
有权
新型苯乙酸衍生物或其药学上可接受的盐，其制备方法和组合物，用于预防或治疗通过激活含有其作为活性成分的T型钙通道引起的疾病
- 专利标题： NOVEL PHENYLACETATE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREOF AND COMPOSITION FOR PREVENTION OR TREATMENT OF DISEASES INDUCED BY ACTIVATION OF T-TYPE CALCIUM ION CHANNEL CONTAINING THE SAME AS AN ACTIVE INGREDIENT
- 专利标题（中）： 新型苯乙酸衍生物或其药学上可接受的盐，其制备方法和组合物，用于预防或治疗通过激活含有其作为活性成分的T型钙通道引起的疾病
-
申请号： US12429004申请日： 2009-04-23
-
公开(公告)号： US20100056545A1公开(公告)日： 2010-03-04
- 发明人: Kye Jung SHIN , Hyung Kook LEE , Eun Joo ROH , Dong Jin KIM , Kyung Il CHOI , Hyewhon RHIM , Hye Jin CHUNG , Seon Hee SEO
- 申请人： Kye Jung SHIN , Hyung Kook LEE , Eun Joo ROH , Dong Jin KIM , Kyung Il CHOI , Hyewhon RHIM , Hye Jin CHUNG , Seon Hee SEO
- 申请人地址： KR Seoul
- 专利权人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- 当前专利权人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- 当前专利权人地址： KR Seoul
- 优先权： KR10-2008-0084563 20080828
- 主分类号： A61K31/4965
- IPC分类号： A61K31/4965 ; C07D235/16 ; C07D295/15 ; C07D211/34 ; A61K31/4184 ; A61K31/445 ; A61P35/00 ; A61P9/12 ; A61P25/00
摘要：
Disclosed herein are a new phenylacetate derivative represented by Chemical Formula 1 or pharmaceutically acceptable salt thereof, a preparation method thereof, and a composition for prevention or treatment of diseases induced by the activation of T-type calcium ion channels containing the same. The composition containing the phenylacetate derivative according to the present invention effectively inhibits the activation of T-type calcium ion channels and may be useful in the prevention or treatment of diseases such as hypertension, cancer, epilepsy, and neurogenic pains induced by the activation of T-type calcium ion channels. wherein, X, R1, and R3 are as defined herein.
信息查询
