A system and method for predicting fatigue life in metal alloys for very high cycle fatigue applications. The system and method are especially useful for cast metal alloys, such as cast aluminum alloys, where a fatigue endurance limit is either non-existent or hard to discern. Fatigue properties, such as fatigue strength in the very high cycle fatigue region, are based on a modified random fatigue limit model, where the very high cycle fatigue strength and infinite life fatigue strength are refined to take into consideration the sizes of the discontinuities and microstructure constituents since the fatigue life scatter depends upon the presence of discontinuities and microstructure constituents. The sizes of the discontinuities and microstructure constituents that can initiate fatigue cracks can be determined with extreme value statistics, then input to the modified random fatigue limit model.