发明申请
US20100015221A1 ORALLY RAPID DISINTEGRATING TABLET PREPARATION COMPRISING FAT-SOLUBLE ACTIVE INGREDIENTS
审中-公开
可快速消除包含脂肪可溶性活性成分的片剂制剂
- 专利标题： ORALLY RAPID DISINTEGRATING TABLET PREPARATION COMPRISING FAT-SOLUBLE ACTIVE INGREDIENTS
- 专利标题（中）： 可快速消除包含脂肪可溶性活性成分的片剂制剂
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申请号： US12097867申请日： 2006-12-20
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公开(公告)号： US20100015221A1公开(公告)日： 2010-01-21
- 发明人: Norishige Takami , Shinsuke Nagira , Yasushi Okada , Noriko Okada , Takayuki Ohwaki , Reiko Nishijima
- 申请人： Norishige Takami , Shinsuke Nagira , Yasushi Okada , Noriko Okada , Takayuki Ohwaki , Reiko Nishijima
- 申请人地址： JP Tokyo
- 专利权人： Eisai R&D Management Co.Ltd.
- 当前专利权人： Eisai R&D Management Co.Ltd.
- 当前专利权人地址： JP Tokyo
- 优先权： JP2005-366791 20051220
- 国际申请： PCT/JP2006/325327 WO 20061220
- 主分类号： A61K9/20
- IPC分类号： A61K9/20 ; A61K31/07 ; A61K31/59 ; A61K31/122 ; A61K31/121 ; A61K31/355 ; A61P43/00
摘要：
The present invention provides an orally rapid disintegrating tablet preparation that contains a high dose of a fat-soluble active ingredient, that exhibits excellent disintegration characteristics in the oral cavity, and that can be produced by a dry tabletting method. The present invention also provides a method of producing an orally rapid disintegrating tablet preparation. The present invention discloses an orally rapid disintegrating tablet preparation that is obtained by tabletting a uniform mixture prepared by mixing saccharide alcohol, crystalline cellulose, and a lubricant with a granule that has been produced by the adsorption of a fat-soluble active ingredient on a porous material.
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