发明申请
- 专利标题： NOVEL ISOINDOLINONE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST T-TYPE CALCIUM CHANNEL AND METHOD FOR PREPARATION THEREOF
- 专利标题（中）： 具有抗T型钙通道的抑制活性的新型茚二酮衍生物及其制备方法
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申请号： US12256701申请日： 2008-10-23
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公开(公告)号： US20100004286A1公开(公告)日： 2010-01-07
- 发明人: Yong Seo CHO , Ae Nim PAE , Hyunah CHOO , Jae Kyun LEE , You Na OH , Hee Sup SHIN , Dong Jin KIM , Hoh Gyu HAHN , Kyung Il CHOI , Ghilsoo NAM , Kye Jung SHIN , Soon Bang KANG , Eun Joo ROH , Dong Yun SHIN , Seon Hee SEO , Hyewhon RHIM , Gyo Chang KEUM , Key-Sun KIM , Chan Seong CHEONG , Eunice Eun-Kyeong KIM , Cheolju LEE , Youngsoo KIM , Kee Hyun CHOI , Kee Dal NAM , Woong Seo PARK , Yong Koo KANG , Hye Jin CHUNG
- 申请人： Yong Seo CHO , Ae Nim PAE , Hyunah CHOO , Jae Kyun LEE , You Na OH , Hee Sup SHIN , Dong Jin KIM , Hoh Gyu HAHN , Kyung Il CHOI , Ghilsoo NAM , Kye Jung SHIN , Soon Bang KANG , Eun Joo ROH , Dong Yun SHIN , Seon Hee SEO , Hyewhon RHIM , Gyo Chang KEUM , Key-Sun KIM , Chan Seong CHEONG , Eunice Eun-Kyeong KIM , Cheolju LEE , Youngsoo KIM , Kee Hyun CHOI , Kee Dal NAM , Woong Seo PARK , Yong Koo KANG , Hye Jin CHUNG
- 申请人地址： KR Seoul
- 专利权人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- 当前专利权人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- 当前专利权人地址： KR Seoul
- 优先权： KR10-2008-0065522 20080707
- 主分类号： A61K31/454
- IPC分类号： A61K31/454 ; C07D401/12 ; A61P35/00 ; A61P9/12 ; A61P25/08
摘要：
Disclosed are isoindolinone derivatives, represented by Chemical Formula 1, having inhibitory activity against T-type calcium channels, pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition comprising the same as an active ingredient. wherein R1˜R6 are as defined in the specification.
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