Invention Application
US20090246776A1 Modulators of scarb-1 for treating acne or hyperseborrhea
审中-公开
用于治疗痤疮或高脂血症的疤痕-1的调节剂
- Patent Title: Modulators of scarb-1 for treating acne or hyperseborrhea
- Patent Title (中): 用于治疗痤疮或高脂血症的疤痕-1的调节剂
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Application No.: US12320166Application Date: 2009-01-21
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Publication No.: US20090246776A1Publication Date: 2009-10-01
- Inventor: Fernand Labrie , Isabelle Carlavan , Pascal Collette , Ezequiel L. Calvo , Jerome Aubert , Johannes Voegel
- Applicant: Fernand Labrie , Isabelle Carlavan , Pascal Collette , Ezequiel L. Calvo , Jerome Aubert , Johannes Voegel
- Applicant Address: FR Biot
- Assignee: GALDERMA RESEARCH & DEVELOPMENT
- Current Assignee: GALDERMA RESEARCH & DEVELOPMENT
- Current Assignee Address: FR Biot
- Priority: FR0653034 20060719
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
An in vitro method for screening candidate compounds for the preventive or curative treatment of acne, includes the determination of the capacity of a compound to modulate the expression or the activity of the SCARB-1 receptor, and the use of modulators of the expression or activity of this receptor for the treatment of acne or skin disorders associated with a hyperseborrhea; methods for the in vitro diagnosis or prognosis of these pathologies are also described.
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