Invention Application
- Patent Title: Crystalline amoxicillin trihydrate powder
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Application No.: US12385444Application Date: 2009-04-08
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Publication No.: US20090208999A1Publication Date: 2009-08-20
- Inventor: Jan Willem Groenendaal , Everardus Johannus Antoinious Maria Leenderts , Thomas Van Der Does
- Applicant: Jan Willem Groenendaal , Everardus Johannus Antoinious Maria Leenderts , Thomas Van Der Does
- Applicant Address: NL Heerlen
- Assignee: DSM IP ASSETS B.V.
- Current Assignee: DSM IP ASSETS B.V.
- Current Assignee Address: NL Heerlen
- Priority: EP03100731.3 20030321; EP03100732.1 20030321
- Main IPC: C12P37/00
- IPC: C12P37/00 ; C07D499/04
Abstract:
The invention relates to crystalline amoxicillin trihydrate powder having a bulk density higher than 0.45 g/ml. The invention also relates to a process for preparing crystalline amoxicillin trihydrate powder, said process comprising: crystallizing amoxicillin trihydrate from a solution containing dissolved amoxicillin; separating the crystals from said solution; and drying the separated crystals, resulting in crystalline powder having a bulk density higher than 0.45 g/ml.
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