发明申请
- 专利标题: Tricyclic Angiotensin II Agonists
- 专利标题(中): 三环血管紧张素II激动剂
-
申请号: US11918240申请日: 2006-04-12
-
公开(公告)号: US20090042931A1公开(公告)日: 2009-02-12
- 发明人: Mathias Alterman , Anders Hallberg , Xiongyu Wu
- 申请人: Mathias Alterman , Anders Hallberg , Xiongyu Wu
- 申请人地址: SE Goteborg
- 专利权人: Vicore Pharma AB
- 当前专利权人: Vicore Pharma AB
- 当前专利权人地址: SE Goteborg
- 国际申请: PCT/GB2006/001319 WO 20060412
- 主分类号: A61K31/4178
- IPC分类号: A61K31/4178 ; A61P1/00 ; A61P9/00 ; C07D409/10 ; A61K31/4155 ; A61K31/437 ; C07D471/04 ; A61K31/4184 ; A61P11/00 ; A61P25/00
摘要:
There is provided compounds of formula I, wherein A, X1, X2, X3, X4, Y1, Y2, Y3, Y4, Z1, Z2, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful as selective agonists of the AT2 receptor, and thus, in particular, in the treatment of inter alia gastrointestinal conditions, such as dyspepsia, IBS and MOF, and cardiovascular disorders.
公开/授权文献
- US08080571B2 Tricyclic angiotensin II agonists 公开/授权日:2011-12-20
信息查询
IPC分类: