发明申请
US20090023762A1 Substituted 2-Aminopyrimidine-4-Ones, Their Pharmaceutical Compositions And Their Use In The Treatment And/Or Prevention Of Ab-Related Pathologies
审中-公开
取代的2-氨基嘧啶-4-酮及其药物组合物及其在治疗和/或预防相关病理学中的应用
- 专利标题: Substituted 2-Aminopyrimidine-4-Ones, Their Pharmaceutical Compositions And Their Use In The Treatment And/Or Prevention Of Ab-Related Pathologies
- 专利标题(中): 取代的2-氨基嘧啶-4-酮及其药物组合物及其在治疗和/或预防相关病理学中的应用
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申请号: US12097316申请日: 2006-12-18
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公开(公告)号: US20090023762A1公开(公告)日: 2009-01-22
- 发明人: Stefan Berg , Jeremy Burrows , Sven Hellberg , Katharina Hogdin , Karin Kolmodin
- 申请人: Stefan Berg , Jeremy Burrows , Sven Hellberg , Katharina Hogdin , Karin Kolmodin
- 申请人地址: SE Sodertalje GB Cambridge
- 专利权人: ASTRAZENECA AB,ASTEX THERAPEUTICS LIMITED
- 当前专利权人: ASTRAZENECA AB,ASTEX THERAPEUTICS LIMITED
- 当前专利权人地址: SE Sodertalje GB Cambridge
- 国际申请: PCT/SE06/01434 WO 20061218
- 主分类号: A61K31/513
- IPC分类号: A61K31/513 ; C07D239/47 ; A61P25/28
摘要:
This invention relates to novel compounds having the structural formula (I) below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel en compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.
公开/授权文献
- US1250233A Tie-mold. 公开/授权日:1917-12-18
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