发明申请
- 专利标题: Piperidine Compound and Process for Preparing the Same
- 专利标题(中): 哌啶化合物及其制备方法
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申请号: US11631282申请日: 2005-07-01
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公开(公告)号: US20090005355A1公开(公告)日: 2009-01-01
- 发明人: Tsutomu Miyake , Takeshi Yamanaka , Hidetoshi Asai , Yoshihiro Terakawa
- 申请人: Tsutomu Miyake , Takeshi Yamanaka , Hidetoshi Asai , Yoshihiro Terakawa
- 申请人地址: JP Osaka-shi
- 专利权人: Tanabe Seiyaku Co., Ltd.
- 当前专利权人: Tanabe Seiyaku Co., Ltd.
- 当前专利权人地址: JP Osaka-shi
- 优先权: JP2004-196360 20040702
- 国际申请: PCT/JP05/12630 WO 20050701
- 主分类号: A61K31/445
- IPC分类号: A61K31/445 ; C07D211/40 ; C07D401/04 ; C07D401/14 ; C07D417/06 ; A61P13/00 ; A61K31/397 ; A61K31/4545 ; A61K31/496 ; A61K31/541
摘要:
The present invention is to provide a piperidine compound represented by the formula [I]: wherein Ring A is an optionally substituted benzene ring, Ring B is an optionally substituted benzene ring, R1 is hydrogen atom or a substituent for amino group, R2 is hydrogen atom, an optionally substituted hydroxyl group, an optionally substituted amino group, an optionally substituted alkyl group, a substituted carbonyl group or a halogen atom, Z is oxygen atom or —N(R3)—, R3 is hydrogen atom or an optionally substituted alkyl group, R4a and R4b may be the same or different, and each is hydrogen atom or an optionally substituted alkyl group, or may be bonded to each other at the both ends to form an alkylene group, or a pharmaceutically acceptable salt thereof, which has an excellent tachykinin receptor antagonistic action.
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