发明申请
US20080306142A1 Isolation, purification and synthesis of procyanidin B2 and uses thereof
有权
原花青素B2的分离，纯化和合成及其用途
- 专利标题： Isolation, purification and synthesis of procyanidin B2 and uses thereof
- 专利标题（中）： 原花青素B2的分离，纯化和合成及其用途
-
申请号： US12119212申请日： 2008-05-12
-
公开(公告)号： US20080306142A1公开(公告)日： 2008-12-11
- 发明人: Gerardo Castillo , Beth Nguyen , Paula Choi , Lesley Larsen , Stephen Lorimer , Alan Snow
- 申请人： Gerardo Castillo , Beth Nguyen , Paula Choi , Lesley Larsen , Stephen Lorimer , Alan Snow
- 主分类号： A61K31/353
- IPC分类号： A61K31/353 ; A61P25/28
摘要：
Methods for the synthesis, isolation, and purification of procyanidin B2 are disclosed. The synthetic methods utilize epicatechin as a starting material and produce procyanidin B2 in high yields. The isolation methods extract procyanidin B2 from a sample of bark powder from plant matter of the genus Uncaria. The isolated and/or synthesized procyanidin B2 is used to treat amyloid disease, such as Alzheimer's disease and Parkinson's disease as well as improve cognitive performance and increase learning and memory in Alzheimer's patients. Pharmaceutical compositions containing the synthesized and/or isolated procyanidin B2 are also disclosed.
公开/授权文献
信息查询
IPC分类:
