The present disclosure is directed to systems and methods which allow for ultrasound parameter estimation to occur at specific advantageous sets of points in a two- or three-dimensional field of view within re-configurable, massively parallel, programmable architectures that can accommodate the input/output streaming, data movement or storage, and computation requirements. In one embodiment, a power efficient system is used for processing the data thereby increasing the ability of the system to be used for hand carried or mobile ultrasound applications. One aspect of the concepts discussed herein is the architectural aspects which provide the ability to simultaneously accept a large number of channels of data characterized by a continuous, simultaneous flow at high sample rates. The input data is routed at high rates to a distributed and large number of processing elements, memory, and connections for simultaneous parameter estimation at multiple points in the field of view. The ability to route the same data to multiple places enables high frame rates and allows for the streaming of data through the architecture.