发明申请
US20080256650A1 Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression
有权
通过靶向TCL1表达在小鼠中建模的人慢性淋巴细胞白血病
- 专利标题： Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression
- 专利标题（中）： 通过靶向TCL1表达在小鼠中建模的人慢性淋巴细胞白血病
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申请号： US12080907申请日： 2008-04-07
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公开(公告)号： US20080256650A1公开(公告)日： 2008-10-16
- 发明人: Carlo M. Croce
- 申请人： Carlo M. Croce
- 申请人地址： US PA Philadelphia
- 专利权人： Thomas Jefferson University
- 当前专利权人： Thomas Jefferson University
- 当前专利权人地址： US PA Philadelphia
- 主分类号： A01K67/027
- IPC分类号： A01K67/027
摘要：
Transgenic animals containing a nucleic acid sequence encoding TCL1 operably linked to transcriptional control sequences directing expression to B cells are described. Such transgenic animals provide a useful animal model system for human B cell chronic lymphocytic leukemia.
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