发明申请
- 专利标题： Piperdine Derivatives as CCR5 Inhibitors
- 专利标题（中）： 哌啶衍生物作为CCR5抑制剂
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申请号： US12114297申请日： 2008-05-02
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公开(公告)号： US20080249111A1公开(公告)日： 2008-10-09
- 发明人: Rainer ALBERT , Nigel Graham Cooke , Gebhard Thoma , Christian Bruns , Francois Nuninger , Markus Streiff , Hans-Gunter Zerwes
- 申请人： Rainer ALBERT , Nigel Graham Cooke , Gebhard Thoma , Christian Bruns , Francois Nuninger , Markus Streiff , Hans-Gunter Zerwes
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 优先权： GB0223223.9 20021007
- 主分类号： A61K31/4545
- IPC分类号： A61K31/4545 ; C07D401/14 ; C07D401/04 ; C07D417/14 ; A61P29/00 ; A61P37/00 ; A61K31/506 ; A61K31/4709
摘要：
Disclosed are compounds of formula I: wherein R1, R2, R3 and X are as defined herein, in free or salt form, which are useful as CCR5 inhibitors, e.g. in the prevention or treatment of disorders mediated by interactions between chemokine receptors and their ligands.
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IPC分类:
