发明申请
US20080220968A1 [1, 2, 4] Triazolo [1, 5-A] Pyrimidine Derivatives as Chromatographic Adsorbent for the Selective Adsorption of Igg
审中-公开
[1,2,4]三氮唑[1,5-A]嘧啶衍生物作为IgG选择性吸附的色谱吸附剂
![[1, 2, 4] Triazolo [1, 5-A] Pyrimidine Derivatives as Chromatographic Adsorbent for the Selective Adsorption of Igg](/docs/US/2008-09-11/US20080220968A1/abs.jpg.600x600.jpg)
- 专利标题： [1, 2, 4] Triazolo [1, 5-A] Pyrimidine Derivatives as Chromatographic Adsorbent for the Selective Adsorption of Igg
- 专利标题（中）： [1,2,4]三氮唑[1,5-A]嘧啶衍生物作为IgG选择性吸附的色谱吸附剂
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申请号： US11994145申请日： 2006-06-26
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公开(公告)号： US20080220968A1公开(公告)日： 2008-09-11
- 发明人: Mathias Alterman , Axen Andreas , Enrique Carredano , Anna Gronberg , Jinyu Zou
- 申请人： Mathias Alterman , Axen Andreas , Enrique Carredano , Anna Gronberg , Jinyu Zou
- 申请人地址： SE UPPSALA
- 专利权人： GE HEALTHCARE BIO-SCIENCES AB
- 当前专利权人： GE HEALTHCARE BIO-SCIENCES AB
- 当前专利权人地址： SE UPPSALA
- 优先权： SE0501560-7 20050705
- 国际申请： PCT/SE2006/000808 WO 20060626
- 主分类号： B01J20/22
- IPC分类号： B01J20/22 ; B01J20/24 ; B01J20/26
![[1, 2, 4] Triazolo [1, 5-A] Pyrimidine Derivatives as Chromatographic Adsorbent for the Selective Adsorption of Igg](/abs-image/US/2008/09/11/US20080220968A1/abs.jpg.150x150.jpg)
摘要：
The present invention relates to a chromatographic adsorbent for selectively adsorbing IgG, comprising the following formula and its corresponding enol-form, wherein X represents O, S, or NH; R1 represents H, C1-6 alkyl, C1-6 alkoxy, C1-6 alkoxy-C1-6 alkyl, Ar, —C(O)NHR3, —C(O)—R3 or halo; R2 represents H, C1-3 alkyl or halo; R3 represents H, C1-6 alkyl, C1-6 alkoxy, C1-6 alkoxy-C1-6 alkyl or Ar; n represents 0, 1, 2 or 3; Y represents a carrier. The present invention also relates to a method of producing said adsorbent as well as use thereof for separating substances by affinity chromatography.
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