发明申请
US20080176897A1 Substituted Quinolone Carboxylic Acids, Their Derivatives, Site of Action, And Uses Thereof
审中-公开
取代喹诺酮羧酸,其衍生物,作用地点及其用途
- 专利标题: Substituted Quinolone Carboxylic Acids, Their Derivatives, Site of Action, And Uses Thereof
- 专利标题(中): 取代喹诺酮羧酸,其衍生物,作用地点及其用途
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申请号: US12032403申请日: 2008-02-15
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公开(公告)号: US20080176897A1公开(公告)日: 2008-07-24
- 发明人: Timothy B.C. Johnstone , Derk J. Hogenkamp , Kelvin W. Gee
- 申请人: Timothy B.C. Johnstone , Derk J. Hogenkamp , Kelvin W. Gee
- 主分类号: A61K31/47
- IPC分类号: A61K31/47 ; A61P25/00
摘要:
Substituted quinolone carboxylic acids and their derivatives are described. These compounds modulate the effect of γ-aminobutyric acid (GABA) via a novel site on the GABAA receptor complex in a therapeutically relevant fashion and may be used to ameliorate CNS disorders amenable to modulation of the GABAA receptor complex.
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