发明申请
- 专利标题: Process for Producing Carbapenem Derivative and Intermediate Crystal Therefor
- 专利标题(中): 生产碳氢化合物衍生物和中间体晶体的方法
-
申请号: US11884195申请日: 2006-02-14
-
公开(公告)号: US20080171864A1公开(公告)日: 2008-07-17
- 发明人: Masaaki Uenaka , Yasuyuki Hozumi , Kouichi Noguchi , Tadafumi Komurasaki
- 申请人: Masaaki Uenaka , Yasuyuki Hozumi , Kouichi Noguchi , Tadafumi Komurasaki
- 优先权: JP2005-037088 20050215; JP2005-193257 20050701
- 国际申请: PCT/JP06/02482 WO 20060214
- 主分类号: C07D477/12
- IPC分类号: C07D477/12
摘要:
An object of the present invention is to provide a carbapenem synthetic intermediate which is advantageous in an industrial process. There are provided a process for producing Compound (I), or a pharmaceutically acceptable salt, or a solvate, or a crystal thereof, comprising reacting Compound (III) and Compound (IV) in the presence of the secondary amine, and a benzyl alcoholated crystal of Compound (I). There are further provided a method of deprotecting Compound (I) with a Pd catalyst, and a crystal of Compound (IV).
公开/授权文献
信息查询