发明申请
- 专利标题： THYMIDINE ANALOGS FOR IMAGING
- 专利标题（中）： 用于成像的THYMIDINE模拟
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申请号： US11923219申请日： 2007-10-24
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公开(公告)号： US20080170993A1公开(公告)日： 2008-07-17
- 发明人: Ananth SRINIVASAN , Ulrike Voigtmann , Mathias Berndt , Keith Grahan , Sabine Zitzmann , Lutz Lehmann , Ansgar Fitzner
- 申请人： Ananth SRINIVASAN , Ulrike Voigtmann , Mathias Berndt , Keith Grahan , Sabine Zitzmann , Lutz Lehmann , Ansgar Fitzner
- 优先权： EP06090198.0 20061025
- 主分类号： A61K51/04
- IPC分类号： A61K51/04 ; A61K31/501 ; C07D405/04 ; A61P35/00
摘要：
The present invention relates to nucleoside analogues and more particularly to labeled nucleoside analogues. It has been found new thymidine analogues can be stably labeled with a detectable label moiety. Further the present invention relates to methods of making above compounds and use of such compounds for diagnostic imaging of tumor cells and/or treatment of proliferative diseases. In addition, the present invention relates to the preparation and use of positron emitting compounds for positron emission tomography (PET). A kit is also disclosed.
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