发明申请
- 专利标题： Malaria Prime/Boost Vaccines
- 专利标题（中）： 疟疾总理/提高疫苗
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申请号： US11665393申请日： 2005-10-13
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公开(公告)号： US20080131461A1公开(公告)日： 2008-06-05
- 发明人: Maria Grazia Pau , Jaap Goudsmit , Joseph D. Cohen , Patrice Dubois , V.Ann Stewart , Donald Heppner
- 申请人： Maria Grazia Pau , Jaap Goudsmit , Joseph D. Cohen , Patrice Dubois , V.Ann Stewart , Donald Heppner
- 申请人地址： NL Leiden BE Rixensart US MD Silver Spring
- 专利权人： Crucell Holland B.V.,GlaxoSmithKline Biologicals S.A.,The Government of the United States as Represented by the Secretary of the Army
- 当前专利权人： Crucell Holland B.V.,GlaxoSmithKline Biologicals S.A.,The Government of the United States as Represented by the Secretary of the Army
- 当前专利权人地址： NL Leiden BE Rixensart US MD Silver Spring
- 优先权： EP04105035.2 20041014
- 国际申请： PCT/EP05/55209 WO 20051013
- 主分类号： A61K39/23
- IPC分类号： A61K39/23 ; A61P43/00
摘要：
The invention relates to novel vaccine regimens in which specific prime/boost regimens are applied using low-neutralized recombinant adenoviral vectors harboring nucleic acids encoding antigens from Plasmodium falciparum and purified recombinant protein vaccines such as RTS,S, in the context of appropriate adjuvants.
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