Provided are a method and apparatus for estimating a center line of an intersection by recognizing a crosswalk on a road input through a camera installed in a vehicle. The apparatus includes a road information providing unit which provides information about a road being traveled based on location information of a traveling vehicle; a crosswalk recognizing unit which recognizes a crosswalk based on an input image of the intersection and the information about the road and obtains a distance from the traveling vehicle to the crosswalk; and an intersection center line estimating unit which estimates the center line of the intersection based on the information about the road and the distance from the traveling vehicle to the crosswalk. Since the center line of the intersection is estimated, the apparatus and method of estimating a center line of an intersection according to the present invention can prevent traffic accidents occurring frequently at an intersection and helps indicate direction information of ‘real vehicle navigation.’