发明申请
US20080009527A1 INHIBITION OF RAF KINASE USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS
失效
使用ARYL和HETEROARYL取代的杂环类URAAS对RAF激酶的抑制作用
- 专利标题: INHIBITION OF RAF KINASE USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS
- 专利标题(中): 使用ARYL和HETEROARYL取代的杂环类URAAS对RAF激酶的抑制作用
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申请号: US11768533申请日: 2007-06-26
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公开(公告)号: US20080009527A1公开(公告)日: 2008-01-10
- 发明人: Jacques Dumas , Uday Khire , Timothy Lowinger , Bernard Riedl , William Scott , Roger Smith , Jill Wood , Holia Hatoum-Mokdad , Jeffrey Johnson , Aniko Redman , Robert Sibley
- 申请人: Jacques Dumas , Uday Khire , Timothy Lowinger , Bernard Riedl , William Scott , Roger Smith , Jill Wood , Holia Hatoum-Mokdad , Jeffrey Johnson , Aniko Redman , Robert Sibley
- 主分类号: A61K31/4439
- IPC分类号: A61K31/4439 ; A61K31/415 ; A61P35/00 ; C07D401/12 ; C07D405/04 ; C07D231/38 ; A61K31/443
摘要:
Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se,
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