发明申请
- 专利标题： Cytokine-expressing cancer immunotherapy combinations
- 专利标题（中）： 细胞因子表达的癌症免疫治疗组合
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申请号： US11728660申请日： 2007-03-27
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公开(公告)号： US20070231298A1公开(公告)日： 2007-10-04
- 发明人: Betty Li , Thomas Du , Karin Jooss
- 申请人： Betty Li , Thomas Du , Karin Jooss
- 申请人地址： US CA South San Francisco
- 专利权人： Cell Genesys, Inc.
- 当前专利权人： Cell Genesys, Inc.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： A61K38/20
- IPC分类号： A61K38/20 ; A61N5/00 ; A61K31/517
摘要：
The present invention in all of its associated aspects provides improved methods and compositions for treating cancer in a mammal based on the sequential administration of the combination of a cytokine-expressing cancer immunotherapy composition and at least one tyrosine kinase inhibitor, wherein administration of the combination results in enhanced therapeutic efficacy relative to administration of the cytokine-expressing cancer immunotherapy composition or at least one tyrosine kinase inhibitor as a monotherapy.
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