Invention Application
US20070116714A1 Vaccine Comprising a Polysaccharide Antigen-Carrier Protein Conjugate and Free Carrier Protein
审中-公开
包含多糖抗原 - 载体蛋白质缀合物和游离载体蛋白的疫苗
- Patent Title: Vaccine Comprising a Polysaccharide Antigen-Carrier Protein Conjugate and Free Carrier Protein
- Patent Title (中): 包含多糖抗原 - 载体蛋白质缀合物和游离载体蛋白的疫苗
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Application No.: US11613797Application Date: 2006-12-20
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Publication No.: US20070116714A1Publication Date: 2007-05-24
- Inventor: Moncef Slaoui , Pierre Hauser
- Applicant: Moncef Slaoui , Pierre Hauser
- Assignee: Smithkline Beecham Biologicals SA
- Current Assignee: Smithkline Beecham Biologicals SA
- Priority: GB9512827.8 19950623; GB9513443.3 19950701; GB9525657.4 19951215; US08/472,639 19950607
- Main IPC: A61K39/295
- IPC: A61K39/295

Abstract:
The present invention relates to combination vaccines comprising a conjugated polysaccharide antigen linked to a carrier protein, and wherein the carrier protein is also present as a free antigen in the vaccine composition, characterised in that the ratio of polysaccharide to protein is from 1:0:3 to 1:2. In particular, the vaccine composition of the present invention relates to a multivalent vaccine, that is a vaccine for the amelioration or treatment of more than one disease state. The present invention also relates to the production and use of such a vaccine in medicine.
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