- 专利标题: Compounds and compositions for prevention of overdose of oxycodone
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申请号: US10953111申请日: 2004-09-30
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公开(公告)号: US20070066537A1公开(公告)日: 2007-03-22
- 发明人: Travis Mickle , Suma Krishnan , James Moncrief , Christopher Lauderback , Thomas Piccariello , Sanjib Bera , Sven Guenther , Wendy Hirschelman
- 申请人: Travis Mickle , Suma Krishnan , James Moncrief , Christopher Lauderback , Thomas Piccariello , Sanjib Bera , Sven Guenther , Wendy Hirschelman
- 申请人地址: US VA Radford 24141
- 专利权人: New River Pharmaceuticals Inc.
- 当前专利权人: New River Pharmaceuticals Inc.
- 当前专利权人地址: US VA Radford 24141
- 主分类号: A61K38/06
- IPC分类号: A61K38/06 ; A61K38/05 ; A61K38/04
摘要:
The invention relates to pharmaceutical compounds and compositions comprised of a chemical moiety attached to an opioid such as oxycodone in a manner that substantially decreases the potential of the opioid to cause overdose. When delivered at the proper dosage the pharmaceutical composition provides therapeutic activity similar to that of the parent active agent. Further the compounds and compositions of the invention are useful in preventing addiction and susceptibility to addiction.
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