发明申请
- 专利标题: Therapeutiv preparation for hematopoietic disease
- 专利标题(中): 造血疾病的治疗剂量
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申请号: US10568033申请日: 2004-08-13
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公开(公告)号: US20070059294A1公开(公告)日: 2007-03-15
- 发明人: Toshihiro Nakajima , Tetsuya Amano , Naoko Yagishita
- 申请人: Toshihiro Nakajima , Tetsuya Amano , Naoko Yagishita
- 国际申请: PCT/JP04/11951 WO 20040813
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C12N5/08 ; A61K38/18
摘要:
The present invention provides therapeutic formulations for hematopoietic diseases comprising as effective ingredient, synoviolin which is reported to be isolated as a synovial cell protein and its gene, and therapeutic methods and such comprising the step of administering the protein or polynucleotide. The present invention also provides as models of hematopoietic diseases, animals whose synoviolin is homozygously deficient and cells derived from such animals; and additionally provides methods that use these models in the screening of therapeutic agents for hematopoietic diseases.
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