发明申请
US20060269979A1 High throughput glycan analysis for diagnosing and monitoring rheumatoid arthritis and other autoimmune diseases
审中-公开
高通量聚糖分析用于诊断和监测类风湿关节炎和其他自身免疫性疾病
- 专利标题： High throughput glycan analysis for diagnosing and monitoring rheumatoid arthritis and other autoimmune diseases
- 专利标题（中）： 高通量聚糖分析用于诊断和监测类风湿关节炎和其他自身免疫性疾病
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申请号： US11411231申请日： 2006-04-26
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公开(公告)号： US20060269979A1公开(公告)日： 2006-11-30
- 发明人: Raymond Dwek , Louise Royle , Pauline Rudd
- 申请人： Raymond Dwek , Louise Royle , Pauline Rudd
- 优先权： WOPCT/IB05/02995 20050624; WOPCT/IB05/02885 20050624
- 主分类号： C12Q1/37
- IPC分类号： C12Q1/37 ; G01N33/00
摘要：
One can identify and quantify one or more glycosylation markers of an autoimmune disease such as rheumatoid arthritis by utilizing quantitative HPLC analysis of glycans which have been released from unpurified glycoproteins. The unpurified glycoproteins can be total glycoproteins or a selection of the total glycoproteins. The identified glycosylation marker can be utilized for monitoring and/or diagnosing the autoimmune disease.
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