发明申请
US20060211682A1 Hexahydrodiazepinones as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
有权
六氢二氮杂酮作为二肽基肽酶-IV抑制剂用于治疗或预防糖尿病
- 专利标题： Hexahydrodiazepinones as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
- 专利标题（中）： 六氢二氮杂酮作为二肽基肽酶-IV抑制剂用于治疗或预防糖尿病
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申请号： US10566235申请日： 2004-07-27
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公开(公告)号： US20060211682A1公开(公告)日： 2006-09-21
- 发明人: Gui-Bai Liang , Tesfaye Biftu , Danqing Feng , Ann Weber
- 申请人： Gui-Bai Liang , Tesfaye Biftu , Danqing Feng , Ann Weber
- 国际申请： PCT/US04/24052 WO 20040727
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; C07D403/02 ; C07D243/02
摘要：
The present invention is directed to hexahydrodiazepinone compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DPP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
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