- 专利标题： Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
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申请号： US11001608申请日： 2004-12-02
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公开(公告)号： US20060079499A1公开(公告)日： 2006-04-13
- 发明人: Jing Wu , Jay Tung , Eugene Thorsett , Michael Pleiss , Jeffrey Nissen , R. Neitz , Lee Latimer , Varghese John , Stephen Freedman , Thomas Britton , James Audia , Jon Reel , Thomas Mabry , Bruce Dressman , Cynthia Cwi , James Droste , Steven Henry , Stacey McDaniel , William Scott , Russell Stucky , Warren Porter
- 申请人： Jing Wu , Jay Tung , Eugene Thorsett , Michael Pleiss , Jeffrey Nissen , R. Neitz , Lee Latimer , Varghese John , Stephen Freedman , Thomas Britton , James Audia , Jon Reel , Thomas Mabry , Bruce Dressman , Cynthia Cwi , James Droste , Steven Henry , Stacey McDaniel , William Scott , Russell Stucky , Warren Porter
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; A61K31/445
摘要：
Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
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