发明申请
- 专利标题: Methods of activating NKT cells
- 专利标题(中): 激活NKT细胞的方法
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申请号: US11218906申请日: 2005-09-02
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公开(公告)号: US20060073118A1公开(公告)日: 2006-04-06
- 发明人: Albert Bendelac , Dapeng Zhou , Luc Teyton , Paul Savage
- 申请人: Albert Bendelac , Dapeng Zhou , Luc Teyton , Paul Savage
- 申请人地址: US IL Chicago US CA La Jolla US UT Provo
- 专利权人: The University of Chicago,The Scripps Research Institute,Brigham Young University
- 当前专利权人: The University of Chicago,The Scripps Research Institute,Brigham Young University
- 当前专利权人地址: US IL Chicago US CA La Jolla US UT Provo
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61K31/739
摘要:
Provided are methods of activating an NKT cell which include a step of contacting the NKT cell with a sufficient amount of isoglobotrihexosylceramide (iGb3) to induce secretion of a cytokine from the NKT cell, stimulate proliferation of the NKT cell or upregulate expression of a cell surface marker on the NKT cell. Methods of activating an NKT cell population in a subject are also provided.
公开/授权文献
- US07998739B2 Methods of activating NKT cells 公开/授权日:2011-08-16
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