发明申请
US20060069099A1 Compounds, compositions and methods for prevention and treatment of inflammatory and immunoregulatory disorders and diseases
失效
用于预防和治疗炎性和免疫调节性疾病和疾病的化合物，组合物和方法
- 专利标题： Compounds, compositions and methods for prevention and treatment of inflammatory and immunoregulatory disorders and diseases
- 专利标题（中）： 用于预防和治疗炎性和免疫调节性疾病和疾病的化合物，组合物和方法
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申请号： US11168005申请日： 2005-06-27
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公开(公告)号： US20060069099A1公开(公告)日： 2006-03-30
- 发明人: Zice Fu , Michael Johnson , An-Rong Li , Andrew Marcus , Julio Medina , Philippe Bergeron , Xiaoqi Chen , Xiaohui Du , Jeffrey Deignan , Jason Duquette , Darin Gustin , Jeffrey Mihalic
- 申请人： Zice Fu , Michael Johnson , An-Rong Li , Andrew Marcus , Julio Medina , Philippe Bergeron , Xiaoqi Chen , Xiaohui Du , Jeffrey Deignan , Jason Duquette , Darin Gustin , Jeffrey Mihalic
- 主分类号： A61K31/525
- IPC分类号： A61K31/525 ; A61K31/519 ; C07D475/02 ; C07D487/02
摘要：
Compounds are provided having the formula: wherein variables Ra, R1, R2, R3, R4, A1, A4, L, Q, X and subscript n as described herein. The subject compounds are useful for treatment of inflammatory and immune conditions and diseases. Compositions and methods of treatment using the subject compounds are also provided. For example, the subject methods are useful for treatment of inflammatory and immune disorders and disease such as multiple sclerosis, rheumatoid arthritis, psoriasis, and inflammatory bowel disease.
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