- 专利标题: Carbapenem antibacterials with gram-negative activity and processes for their preparation
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申请号: US11150428申请日: 2005-06-10
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公开(公告)号: US20060069081A1公开(公告)日: 2006-03-30
- 发明人: Woo-Baeg Choi , Ewa Kowalik
- 申请人: Woo-Baeg Choi , Ewa Kowalik
- 主分类号: A61K31/407
- IPC分类号: A61K31/407 ; C07D487/08
摘要:
The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents.
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