发明申请
- 专利标题： Substituted aryl-amine derivatives and methods of use
- 专利标题（中）： 取代的芳基 - 胺衍生物和使用方法
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申请号： US11185556申请日： 2005-07-19
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公开(公告)号： US20060040966A1公开(公告)日： 2006-02-23
- 发明人: Chester Yuan , Kevin Yang , Simon Van Der Plas , Babak Riahi , Michele Potashman , Vinod Patel , Rana Nomak , Aiwen Li , Qi Huang , Jean-Christophe Harmange , Benny Askew
- 申请人： Chester Yuan , Kevin Yang , Simon Van Der Plas , Babak Riahi , Michele Potashman , Vinod Patel , Rana Nomak , Aiwen Li , Qi Huang , Jean-Christophe Harmange , Benny Askew
- 主分类号： A61K31/517
- IPC分类号： A61K31/517 ; A61K31/4433 ; C07D405/02 ; C07D401/02
摘要：
Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds of Formula I and II wherein R, R1 and R2 for each formula are defined herein. The invention further includes analogs, prodrugs and pharmaceutically acceptable salts and derivatives of Formulas I and II, as well as pharmaceutical compositions, medicaments and methods thereof for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
公开/授权文献
- US07507748B2 Substituted aryl-amine derivatives and methods of use 公开/授权日：2009-03-24
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