发明申请
- 专利标题: Method for the continuous production of tetra-substituted ureas
- 专利标题(中): 连续生产四取代脲的方法
-
申请号: US10520402申请日: 2003-07-03
-
公开(公告)号: US20050261524A1公开(公告)日: 2005-11-24
- 发明人: Jochen Henkelmann , Theodor Weber , Thorsten Rohde , Ralph Busch
- 申请人: Jochen Henkelmann , Theodor Weber , Thorsten Rohde , Ralph Busch
- 申请人地址: DE Ludwigshafen D-67056
- 专利权人: BASF AKTIENGESELLSCHAFT
- 当前专利权人: BASF AKTIENGESELLSCHAFT
- 当前专利权人地址: DE Ludwigshafen D-67056
- 优先权: DE102310858 20020710
- 国际申请: PCT/EP03/07083 WO 20030703
- 主分类号: C07C273/18
- IPC分类号: C07C273/18 ; C07C275/06
摘要:
The invention relates to a process for the preparation of tetrasubstituted ureas by reaction of the corresponding amines with phosgene in the presence of an aqueous inorganic base at a temperature in the range from 0 to 150° C., which comprises: feeding the corresponding amine, the phosgene and the aqueous inorganic base on average continuously to the reaction apparatus, forming a two-phase system in the reaction apparatus through the choice of the tetrasubstituted ureas to be prepared, through the mixing ratios of the substances and substance mixtures to be fed in, through the temperature during the reaction and, where appropriate, through the feed of an organic solvent which is not completely miscible with water, and discharging the reaction mixture on average continuously from the reaction apparatus.
公开/授权文献
信息查询