Invention Application
US20050222140A1 Phenylalanine derivatives as depeptidyl peptidase inhibitors for the treatment or prevention of diabetes
有权
苯丙氨酸衍生物作为二肽基肽酶抑制剂，用于治疗或预防糖尿病
- Patent Title: Phenylalanine derivatives as depeptidyl peptidase inhibitors for the treatment or prevention of diabetes
- Patent Title (中): 苯丙氨酸衍生物作为二肽基肽酶抑制剂，用于治疗或预防糖尿病
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Application No.: US10481352Application Date: 2003-11-03
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Publication No.: US20050222140A1Publication Date: 2005-10-06
- Inventor: Vincent Colandrea , Scott Edmondson , Robert Mathvink , Anthony Mastracchio , Ann Weber , Jinyou Xu
- Applicant: Vincent Colandrea , Scott Edmondson , Robert Mathvink , Anthony Mastracchio , Ann Weber , Jinyou Xu
- Priority: US60424483 20020711; US60501232 20030619
- International Application: PCT/US03/34924 WO 20031103
- Main IPC: A61K31/395
- IPC: A61K31/395 ; A61K31/40 ; A61K31/445 ; A61K31/54 ; A61P3/10 ; C07D205/04 ; C07D207/10 ; C07D211/30 ; C07D211/38 ; C07D213/64 ; C07D279/12 ; C07D295/18 ; C07D295/185 ; C07D401/10 ; C07D401/12 ; C07D403/06 ; C07D403/10 ; C07D403/12 ; C07D413/10 ; C07D413/12 ; C07D417/10 ; C07D471/04 ; C07D487/04
Abstract:
The present invention is directed to phenylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Public/Granted literature
- US07157490B2 Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes Public/Granted day:2007-01-02
Information query
