发明申请
- 专利标题： Serine protease inhibitors
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申请号： US11088511申请日： 2005-03-24
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公开(公告)号： US20050186198A1公开(公告)日： 2005-08-25
- 发明人: Ignacio Aliagas-Martin , Dean Artis , Michael Dina , John Flygare , Richard Goldsmith , Regina Munroe , Alan Olivero , Richard Pastor , Thomas Rawson , Kirk Robarge , Daniel Sutherlin , Kenneth Weese , Aihe Zhou , Yan Zhu
- 申请人： Ignacio Aliagas-Martin , Dean Artis , Michael Dina , John Flygare , Richard Goldsmith , Regina Munroe , Alan Olivero , Richard Pastor , Thomas Rawson , Kirk Robarge , Daniel Sutherlin , Kenneth Weese , Aihe Zhou , Yan Zhu
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 主分类号： C07D333/34
- IPC分类号： C07D333/34 ; A61K31/18 ; A61K31/196 ; A61K31/216 ; A61K31/381 ; A61P7/02 ; A61P9/10 ; C07C257/18 ; C07C311/05 ; C07C311/08 ; C07C311/13 ; C07C311/18 ; C07C311/29 ; C07C311/51 ; A61K38/48 ; A61K31/445 ; A61K31/54 ; A61K31/60
摘要：
Compounds having the structure shown below are useful to inhibit serine protease enzymes, such as TF/factor VIIa, factor Xa, thrombin and kallikrein. These compounds may be used in methods of preventing and/or treating clotting disorders.
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