发明申请
US20050182046A1 Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
审中-公开
环烷基，内酰胺，内酯和相关化合物，包含其的药物组合物，以及通过使用这些化合物抑制β-淀粉样蛋白肽释放和/或其合成的方法
- 专利标题： Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
- 专利标题（中）： 环烷基，内酰胺，内酯和相关化合物，包含其的药物组合物，以及通过使用这些化合物抑制β-淀粉样蛋白肽释放和/或其合成的方法
-
申请号： US10777247申请日： 2004-02-13
-
公开(公告)号： US20050182046A1公开(公告)日： 2005-08-18
- 发明人: Jing Wu , Jay Tung , Eugene Thorsett , Michael Pleiss , Jeffrey Nissen , R. Neitz , Lee Latimer , Varghese John , Stephen Freedman , Thomas Britton , James Audia , Jon Reel , Thomas Mabry , Bruce Dressman , Cynthia Cwi , James Droste , Steven Henry , Stacey McDaniel , William Scott , Russell Stucky , Warren Porter
- 申请人： Jing Wu , Jay Tung , Eugene Thorsett , Michael Pleiss , Jeffrey Nissen , R. Neitz , Lee Latimer , Varghese John , Stephen Freedman , Thomas Britton , James Audia , Jon Reel , Thomas Mabry , Bruce Dressman , Cynthia Cwi , James Droste , Steven Henry , Stacey McDaniel , William Scott , Russell Stucky , Warren Porter
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; A61K31/4015 ; A61K31/445 ; A61K31/55 ; A61K38/04 ; A61K38/05 ; A61P25/28 ; C07D223/18 ; C07D471/04 ; C07D471/06 ; C07D471/08
摘要：
Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
信息查询
