发明申请
- 专利标题： Malonamide derivatives
- 专利标题（中）： 丙二酰胺衍生物
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申请号： US10933177申请日： 2004-09-02
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公开(公告)号： US20050054633A1公开(公告)日： 2005-03-10
- 发明人: Alexander Flohr , Guido Galley , Roland Jakob-Roetne , Eric Kitas , Jens-Uwe Peters , Wolfgang Wostl
- 申请人： Alexander Flohr , Guido Galley , Roland Jakob-Roetne , Eric Kitas , Jens-Uwe Peters , Wolfgang Wostl
- 优先权： EP03019683.6 20030909
- 主分类号： A61K31/335
- IPC分类号： A61K31/335 ; A61K31/55 ; A61K31/5513 ; C07D223/16 ; C07D223/20 ; C07D243/24 ; C07D273/00 ; C07D313/14
摘要：
The invention relates to malonamide derivatives of formula wherein each of the variables are as defined herein and to pharmaceutically acceptable acid addition salts, optically pure enantiomers, racemates and diastereomeric mixtures thereof. These compounds are γ-secretase inhibitors and may be used for the treatment of Alzheimer's disease.
公开/授权文献
- US07160875B2 Malonamide derivatives 公开/授权日：2007-01-09
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